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Dr. Hao-Hua Wu Offers Improved Treatment for Cervical Disc Disease Successful Surgery with Mobi-C Cervical Disc at Two Levels Allows Patient to Maintain Neck Motion

Mobi-C® Cervical Disc replaces diseased discs in the neck and is designed to maintain motion similar to the natural cervical spine. Traditionally, the same patient would have received a fusion. Fusion surgery, while also replacing diseased discs in the neck, is designed to stop movement at the operated levels. Often times when you fuse, stress can be transferred to the adjacent discs, which can result in additional surgeries or accelerated disc degeneration.

Mobi-C received FDA approval in 2013, making it the first cervical disc in the U.S. approved to treat more than one level of the cervical spine. Upon approval, Mobi-C was non-inferior to fusion at one level and SUPERIOR to fusion at two levels.

In 2018 the FDA approved the 7 year clinical results, confirming that Mobi-C at two levels continued to demonstrate superiority over fusion based on overall study success. Those patients who received two level cervical disc replacement during the trial returned to work on average approximately three weeks earlier as compared to the fusion patients.

Upon completion of the 7-year FDA IDE study, follow-up continued on a subset of Mobi-C patients with the goal of obtaining 10-year follow-up on all eligible patients. At 10 years, all patient-reported outcomes of Mobi-C recipients were equivalent to or improved from 7 years. Recipients of Mobi-C reported improved Neck Disability Index (NDI) Scores, improved neck pain, and improved arm pain. In addition, no subsequent surgery at an adjacent level occurred between the 7 year and 10 year follow up.1,2

In 2023, ZimVie announced that over 200,000 Mobi-C Cervical Discs have been implanted globally. This milestone aligns with the ten-year anniversary of Mobi-C FDA approval for treatment of one and two levels of the cervical spine.

I am passionate about motion preservation in the right indications, and I am very happy to be able to offer my patients the state-of-the-art cervical disc replacement procedure,” said Dr. Hao-Hua Wu, an Assistant Professor of Orthopaedic Surgery at UCI Health.

About the Mobi-C Cervical Disc

Mobi-C is the first cervical disc prosthesis approved by the FDA for reconstruction of a cervical disc at both one and two levels (C3-C7). Mobi-C is a cobalt chromium alloy and polyethylene mobile-bearing prosthesis that is inserted in a single step, without requiring bone chiseling or other vertebral anchorage such as screws or keels. The Mobi-C Cervical Disc Prosthesis is indicated in skeletally mature patients for reconstruction of the disc from C3-C7 following discectomy at one level or two contiguous levels for intractable radiculopathy (arm pain and/or neurological deficit) with or without neck pain or myelopathy due to abnormality localized to the level of the disc space and at least one of the following conditions confirmed by radiographic imaging (CT, MRI or X-rays): herniated nucleus pulposus, spondylosis (defined by the presence of osteophytes) and/or visible loss of disc height compared to adjacent levels. The Mobi-C Cervical Disc Prosthesis is implanted using an anterior approach. Patients should have failed at least six weeks of conservative treatment or demonstrated progressive signs or symptoms despite nonoperative treatment prior to implantation of the Mobi-C Cervical Disc Prosthesis.

Book your consultation now with Dr. Wu at UCI Health:

  • Hao-Hua Wu, M.D.

    101 The City Drive South
    Pavilion 3 Building 29A
    Orange, CA 92868

  • UCI Health — Tustin

    1451 Irvine Blvd.
    Tustin, CA 92780

  • UCI Health — Newport Beach

    2161 San Joaquin Hills Road
    Newport Beach, CA 92660

  • UCI Health — Yorba Linda

    18637 Yorba Linda Blvd.
    Yorba Linda, CA 92886

Useful Links

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  • University of California San Francisco Department of Orthopaedic Surgery
  • Harvard Medical School
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  • American Academy of Orthopaedic Surgeons
  • AOSpine
  • North American Spine Society
  • Global Spine Research Initiative